Saturday, January 25, 2020

Defences Against Pathogenic Organisms

Defences Against Pathogenic Organisms Bacteria Defined in the dictionary as ‘a bacterium, virus, or other microorganism that can cause disease. Which can then be divided into different categories, bacterium, virus, fungus and finally protozoa. Bacteria can be in the form of many sizes and can cause such things as cholera and typhoid fever. The virus type of pathogens are much smaller than bacteria and have a ‘fragment of genetic material inside a protective protein coat’. They are also especially common of causing influenza. Fungi can look like mould and can cause such things like athlete’s foot. Protozoa can come in the form of contaminated food and some are parasites. They are organisms that live in or on, certain things. A very serious example of this type, is malaria. Features Virus Bacteria Fungus Protozoa Nutrition Do not have or need nutrition and do not eat anything Mostly are heterotrophic, which means they live from and off other organisms. Also ‘At an elementary level, the nutritional requirements of a bacterium such as E. coli are revealed by the cells elemental composition’. Absorbs nutrients like carbohydrates (glucose, fructose, xylose, sucrose) and also starches, cellulose, hemicelluloses and proteins. Require organic materials ‘which may be particulate or in solution’. They are holozoic. Reproduction Rely on host cells for the ‘machinery needed to survive and reproduce.’ Once finding a host, it then looks for host cells to take over and ‘slowly implants its genetic makeup into the cell.’ Reproduce by the process binary fission. Where the cells split into and divides into 2 identical daughter cells and ‘When conditions are favourable such as the right temperature and nutrients are available, some bacteria like Escherichia coli can divide every 20 minutes’. Environmental conditions can influence how this happens and usually sexual or asexual reproduction are the main methods. Some yeasts and funguses thrive in warm environments, and can multiply at an extremely fast pace. Also may be a sexual, and also reproduction by binary fission is very common here. Structure Their structure consists of a strand of nucleic acid, which is either DNA or RNA. Then it has something called a ‘capsid’ which is a protective protein coat. Bacteria have a cell wall with no nucleus and have two types of DNA- plasmid and chromosomal. Some are unicellular but most are multicellular which have cell walls and they are made of chitin. Single celled organisms that have a cell membrane, nucleus, cytoplasm and vacuole. Sources used Bbc bitesize . (2015). Whats in a cell?. Available: http://www.bbc.co.uk/schools/gcsebitesize/science/add_edexcel/cells/cells1.shtml. Last accessed 17th march 2015. Chris Sherwood . (2015). How Do Viruses Reproduce?. Available: http://www.ehow.com/how-does_4567511_viruses-reproduce.html. Last accessed 17th march 2015. Constantine John Alexopoulos . (2015). Fungus . Available: http://www.britannica.com/EBchecked/topic/222357/fungus/57967/Nutrition. Last accessed 17th march 2015. G gingham. (2014). Bacteria. Available: http://www.microbiologyonline.org.uk/about-microbiology/introducing-microbes/bacteria. Last accessed 17th march 2015 Kenneth Todar. (2014). Nutrition and Growth of Bacteria. Available: http://textbookofbacteriology.net/nutgro.html. Last accessed 17th march 2015. Robert G Yaeger . (2015). Protozoa . Available: http://www.ncbi.nlm.nih.gov/books/NBK8325/. Last accessed 17th march 2015. How does the body defend itself against pathogens which cause infectious disease? Pathogens can enter the body by ‘route of transmission’. People can pick up a pathogen by person to person contact with touch, saliva and contaminated blood or bodily fluids. Pathogens can also be transmitted through foods, water, insects and fomites. Food can be contaminated by unclean hands, unclean utensils, and is cross contaminated. Water can be contaminated by human or animal faeces which spreads the infection when drank, and insects can also carry a pathogen for example malaria. Lastly fomites are actually non-living but can spread pathogens by way of bedding, toys and wire for example. A common one is also athlete’s foot. Airborne pathogens enter through the nose and mouth of the body as you breathe, and food pathogens enter through your mouth and then into the digestive system. Also they can also enter into the blood stream through ‘vectors’ which is transmitted by mosquitos, fleas, ticks and contaminated needles. Breaks in the skin are also ways of entering. From the outside of the body the physical defences and barriers we have to help us are the skin which is a physical barrier, clotting which if skin is broken the blood clots to stop any entering, sebaceous and sweet glands that produce chemicals that kill bacteria, lysozyme which is in saliva and tears that kills bacteria, mucous membranes which secretes mucous and traps pathogens, nasal hairs that remove the organisms from the air, cilia force mucus to the pharynx for swallowing, hydrochloric acid kills microorganisms, and the vagina produces lactic acid which stops growth of pathogens and has a low ph and mucous membranes that kill bacteria. If the physical barriers cannot defend against pathogens, then a ‘second defence line’ takes over which is a general defence system. Phagocytes that are white blood cells engulf pathogens and macrophages which are a longer living phagocytes help digest the bacteria and protect the body. Substances that are produced by other proteins called complement defence proteins can help fight pathogens, and are produced in response to knowing the presence of foreign materials in the body and ‘burst or engulf the pathogen.’ Also interferons are proteins that help prevent spread of the virus, and inflammation are infected cells that produce a chemical histamine, and help more white blood cells get to the area to help fight infection. Antibodies play a special part to fight pathogens as they are ‘lymphocytes that produce antibodies as a result of antigens.’ These are proteins in the group called immunoglobulins. Each antigen will only stimulate the production of one specific antibody that will fit into its receptor area. This is called natural active induced immunity. It is protection gained against a particular pathogen by the production of specific antibodies after the antigen on the pathogen has been detected.’ Pathogens are prevented from entering a host cell by antibodies binding to the antigens which are on the surface of the pathogen, and pathogens can be burst by antibodies activating the complement system. -see diagram here T and B cells are lymphocytes, while t cells mature in the thymus gland and b cells mature in the bone marrow. The point of t cells, is that they are defenders that are activated in the thymus gland and do not actually produce antibodies but do help to protect in other ways. They have helper t cells which recognise antigens especially macrophages that multiply and enlarge and form helper t cells that produce chemicals (interferon) that then stimulate the forming of b cells. Then they stimulate the reproduction of killer t cells. Killer t cells produce and destroy abnormal body cells and release a protein named perforin which form pores in the membranes of the cells they attack and ‘Water and ions from the surroundings flow into the cells and burst them. This is called lysis.’ Suppressor t cells inhibit working after the pathogen is destroyed, and memory t cells survive for a long time and stimulate memory b cells to produce antibodies. B cells work in the lymphatic syste m ‘especially the spleen and lymph nodes’ and work on just one specific antigen and comes into contact with an antigen to then reproduce at a rapid pace which are plasma cells. They are very efficient and effective, but do only last a few days. Most b cells die within a few days like said before, but some do stay alive which are referred to as memory b cells and ‘When the same antigen becomes present in the organism these memory B-cells are already there to begin the production of plasma cells and antibodies.’ Which is secondary B cell response. These are more powerful because they are produced faster, more are produced, and they are produced to a smaller amount of antigen. The primary response of the immune system to infection is on the first time it is encountered and ‘Depending on the nature of the antigen and the site of entry this response can take up to 14 days to resolve and leads to the generation of memory cells with a high specificity for the inducing antigen.’ As soon as a foreign antigen is exposed, an even though no antibodies are produced activated b cells differentiate to plasma cells. Secondary response is the response to the antigen where there is a large production of amounts of antibodies. Memory cells help generate what type of antibodies to produce during an immune response. It is like a B cell that keeps a memory of the older lymphocyte that was generated when there was an immune response for a specific antigen. They act as guardians waiting for the return of the same antigen so they can recruit the immune system and mount an attack sooner and more aggressively. Sources used for this TAQ *Alexander A Ademokun. (2015). Immune Responses: Primary and Secondary. Available: http://www.els.net/WileyCDA/ElsArticle/refId-a0000947.html. Last accessed 17th march 2015. *bbc bitesize . (2015). Defending against infection. Available: http://www.bbc.co.uk/schools/gcsebitesize/science/aqa_pre_2011/human/defendingagainstinfectionrev1.shtml. Last accessed 17th march 2015. *ico praver . (2015). Routes of Transmission. Available: http://www.microbiologyonline.org.uk/about-microbiology/microbes-and-the-human-body/routes-of-transmission . Last accessed 17th march 2015. * S Detea . (2015). secondary response . Available: http://thesciencedictionary.org/secondary-immune-response/. Last accessed 17th march 2015. Immunity Natural Acquired Similarities Resist a specific disease. ‘Inflammation.’ Resist a specific disease. Inflammation.’ Involve the action of antibodies in the body somehow Involve the action of antibodies in the body somehow Technically use white blood cells to try and fight pathogen/ infection Technically use white blood cells to try and fight pathogen/ infection Differences Natural is from birth, and get it from being born and is ‘genetic’. You acquire this immunity after exposure to a pathogen. Remains throughout your life Can be short lived or life long This immunity has barriers that prevent entry of foreign agents Consists of special t and b cells and also antibodies that are in body fluid Response is immediate Response can take a few days, and is not immediate Sources used *Christopher Hassell. (2014). Acquired Immunity. Available: http://greaterimmunity.com/Files/acquired_immunity.html. Last accessed 18th march 2015 *Garland science . (2015). The immune system in health and disease. Available: http://www.ncbi.nlm.nih.gov/books/NBK27090/. Last accessed 18th march 2015 References and bibliography Alexander A Ademokun. (2015). Immune Responses: Primary and Secondary. Available: http://www.els.net/WileyCDA/ElsArticle/refId-a0000947.html. Last accessed 17th march 2015. Ananya Mandal. (2014). Cholera Transmission. Available: http://www.news-medical.net/health/Cholera-Transmission.aspx. Last accessed 16th march 2015. Arthur Schoenstadt. (2012). Malaria Transmission. Available: http://malaria.emedtv.com/malaria/malaria-transmission.html. Last accessed 16th march 2015. Bbc bitesize. (2015). Defending against infection. Available: http://www.bbc.co.uk/schools/gcsebitesize/science/aqa_pre_2011/human/defendingagainstinfectionrev1.shtml. Last accessed 17th march 2015. Bbc bitesize. (2015). Whats in a cell?. Available: http://www.bbc.co.uk/schools/gcsebitesize/science/add_edexcel/cells/cells1.shtml. Last accessed 17th march 2015. Centers for Disease Control and Prevention. (2014). Influenza. Available: http://www.cdc.gov/flu/keyfacts.htm. Last accessed 16th march 2015. Eric J. Nelson, Jason B. Harris, J. Glenn Morris, Jr, Stephen B. Calderwood Andrew Camilli. (2014). Life cycle of pathogenic Vibrio cholerae.. Available: http://www.nature.com/nrmicro/journal/v7/n10/fig_tab/nrmicro2204_F2.html. Last accessed 16th march 2015. Christopher Hassell. (2014). Acquired Immunity. Available: http://greaterimmunity.com/Files/acquired_immunity.html. Last accessed 18th march 2015 Chris Sherwood. (2015). How Do Viruses Reproduce?. Available: http://www.ehow.com/how-does_4567511_viruses-reproduce.html. Last accessed 17th march 2015. Constantine John Alexopoulos. (2015). Fungus . Available: http://www.britannica.com/EBchecked/topic/222357/fungus/57967/Nutrition. Last accessed 17th march 2015. Garland science. (2015). The immune system in health and disease. Available: http://www.ncbi.nlm.nih.gov/books/NBK27090/. Last accessed 18th march 2015 G gingham. (2014). Bacteria. Available: http://www.microbiologyonline.org.uk/about-microbiology/introducing-microbes/bacteria. Last accessed 17th march 2015 Great Ormond. (2015). Infection prevention and control. Available: http://www.gosh.nhs.uk/parents-and-visitors/coming-to-hospital/infection-control-and-prevention/. Last accessed 18th march 2015. Ico praver. (2015). Routes of Transmission. Available: http://www.microbiologyonline.org.uk/about-microbiology/microbes-and-the-human-body/routes-of-transmission . Last accessed 17th march 2015. Kalyan Das. (2015). Influenza A life cycle.. Available: http://www.nature.com/nsmb/journal/v17/n5/fig_tab/nsmb.1779_F1.html. Last accessed 16th march 2015. Kenneth Todar. (2014). Nutrition and Growth of Bacteria. Available: http://textbookofbacteriology.net/nutgro.html. Last accessed 17th march 2015. Kristeen Cherney. (2014). What is Cross Infection?. Available: http://www.healthline.com/health/cross-infection#Overview1. Last accessed 18th march 2015. Lisa minu. (2014). Understanding Athletes Foot . Available: http://www.webmd.com/skin-problems-and-treatments/guide/understanding-athletes-foot-basics. Last accessed 16th march 2015. Public Health England. (2015). Infection control: New best practice guide will bolster fight against healthcare associated infections See more at: http://www.buildingbetterhealthcare.co.uk/news/article_page/Infection_control_New_. Available: http://www.buildingbetterhealthcare.co.uk/news/article_page/Infection_control_New_best_practice_guide_will_bolster_fight_against_healthcare_associated_infections/71006. Last accessed 18th march 2015 Robert G Yaeger. (2015). Protozoa . Available: http://www.ncbi.nlm.nih.gov/books/NBK8325/. Last accessed 17th march 2015. S Detea . (2015). Secondary response . Available: http://thesciencedictionary.org/secondary-immune-response/. Last accessed 17th march 2015. Thomas Urbauer. (2014). What Is the Life Cycle of Tinea Pedis? . Available: http://www.ehow.com/about_6513541_life-cycle-tinea-pedis_.html. Last accessed 16th march 2015. Toni Rizzo. (2015). Hospital-Acquired Infections . Available: http://www.encyclopedia.com/topic/Cross_infection.aspx. Last accessed 18th march 2015 WHO. (2015). 10 facts on cholera. Available: http://www.who.int/features/factfiles/cholera/en/. Last accessed 16th march 2015.

Friday, January 17, 2020

Finance 3220 Problem Set 1

What is the present value of $150,000 to be received 8 years from today if the discount rate is 11 percent? Question 1 options: | A)|   $65,088. 97| | B)|   $71,147. 07| | C)|   $74,141. 41| | D)|   $79,806. 18| | E)|   $83,291. 06 | Question 2 (2 points) According to the Rule of 72, you can do which one of the following? Question 2 options: | A)|   double your money in five years at 7. 2 percent interest| | B)|   double your money in 7. 2 years at 8 percent interest| | C)|   double your money in 8 years at 9 percent interest| | D)|   triple your money in 7. years at 5 percent interest| | E)|   triple your money at 10 percent interest in 7. 2 years  | Question 3 (2 points) On your ninth birthday, you received $300 which you invested at 4. 5 percent interest, compounded annually. Your investment is now worth $757. How old are you today? Question 3 options: | A)|   age 29| | B)|   age 30| | C)|   age 31| | D)|   age 32| | E)|   age 33| Question 4 (2 poin ts) You just received a $5,000 gift from your grandmother. You have decided to save this money so that you can gift it to your grandchildren 50 years from now.How much additional money will you have to gift to your grandchildren if you can earn an average of 8. 5 percent instead of just 8 percent on your savings? Question 4 options: | A)|   $47,318. 09| | B)|   $52,464. 79| | C)|   $55,211. 16| | D)|   $58,811. 99| | E)|   $60,923. 52 | Question 5 (2 points) Shelley won a lottery and will receive $1,000 a year for the next ten years. The value of her winnings today discounted at her discount rate is called which one of the following? Question 5 options: | A)|   single amount| | B)|   future value| | C)|   present value| D)|   simple amount| | E)|   compounded value | Question 6 (2 points) Andy deposited $3,000 this morning into an account that pays 5 percent interest, compounded annually. Barb also deposited $3,000 this morning into an account that pays 5 percent interest, compounded annually. Andy will withdraw his interest earnings and spend it as soon as possible. Barb will reinvest her interest earnings into her account. Given this, which one of the following statements is true? Question 6 options: | A)|   Barb will earn more interest the first year than Andy will. | B)|   Andy will earn more interest in year three than Barb will. | | C)|   Barb will earn interest on interest. | | D)|   After five years, Andy and Barb will both have earned the same amount of interest. | | E)|   Andy will earn compound interest. | Question 7 (2 points) You invested $1,650 in an account that pays 5 percent simple interest. How much more could you have earned over a 20-year period if the interest had compounded annually? Question 7 options: | A)|   $849. 22| | B)|   $930. 11| | C)|   $982. 19| | D)|   $1,021. 15| | E)|   $1,077. 94 | Question 8 (2 points)A year ago, you deposited $30,000 into a retirement savings account at a fixed rate of 5. 5 percent. Today, you could earn a fixed rate of 6. 5 percent on a similar type account. However, your rate is fixed and cannot be adjusted. How much less could you have deposited last year if you could have earned a fixed rate of 6. 5 percent and still have the same amount as you currently will when you retire 38 years from today? Question 8 options: | A)|   $2,118. 42 less| | B)|   $3,333. 33 less| | C)|   $5,417. 09 less| | D)|   $7,274. 12 less| | E)|   $9,234. 97 less  |Question 9 (2 points) You are investing $100 today in a savings account at your local bank. Which one of the following terms refers to the value of this investment one year from now? Question 9 options: | A)|   future value| | B)|   present value| | C)|   principal amounts| | D)|   discounted value| | E)|   invested principal | Question 10 (2 points) One year ago, you invested $1,800. Today it is worth $1,924. 62. What rate of interest did you earn? Question 10 options: | A)|   6. 59 percent| | B)|   6. 67 percent| | C)|   6. 88 percent| | D)|   6. 92 percent| | E)|   7. 01 percent |

Thursday, January 9, 2020

Public Security Vs. Privacy - 1288 Words

â€Å"Big brother is watching you.† In the book Nineteen Eighty-Four (Orwell, 1948), the author presented a repressed and horrible Utopia with Surveillance state, Big Brother, doublespeak and thoughtcrimes. Today, many people believe that the book Nineteen Eighty-Four has already become a prophecy in the United States because they are being surrounded by numerous cameras. Although January Mughal in her article â€Å"National Security Vs. Privacy In The Modern Age†(2016), insisted that surveillance is necessary to maintain the security of United States, but it is doubtful based on many research because the uses of government surveillance are inefficient, the surveillance cannot stop terrorist attacks, and the ethical issues of surveillance†¦show more content†¦The surveillance is not as good as US government said, although government announced that the surveillance prevents over 50 potential terrorist attacks in the United States, the authors of the report NSAâ €™s Bulk Surveillance Programs Stop Terrorists? Showed that NSA surveillance only initiated 7.5% investigation of terrorism, of which a few of investigations are legal compared to traditional investigative methods which initiated 60% of the investigation, In addition, NSA Director Alexander admitted that the bulk collection of American phone date had only prevented one known terrorist attack. Thus, government surveillance has low efficiency. What is more, the bulk collection is not accurate, Innocent jokes or statement can mislead government surveillance, a man named Joe Lipari Spent two years on fighting charge because the paraphrased a quote form fill Fight Club. And also the targets of surveillance are ambiguous, during the war I, government surveillance targeted on precursors to the FBI, the Bureau of the investigation, war critics and even anti-draft activists who are the innocent citizens. January Mughal mentioned that the surveillance still necessary, in spite of its disa dvantages, to protect our security and bring justice if it focuses on suspected terrorists or person of thereat, demonstrates a warrant and is put in public spaces. However, it is not that easy to protectShow MoreRelatedThe Security Of Our Nation1359 Words   |  6 Pagesour nation was established, security was not an issue. The towns then were little and almost everyone knew their fellow neighbors and what was going on. 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Wednesday, January 1, 2020

History Of The United States Health Care System Essay

rehend the PPACA, one must understand the history of the United States’ health care system. The most successful and known reform would be the passage of Medicare and Medicaid. President Johnson’s main objective with his program was to provide health insurance to those over 65 years old, who otherwise wouldn’t be able to receive coverage due to retirement or being financially unfit to purchase health insurance. It has since been expanded to cover those with disabilities, and lower income families (â€Å"Overview,† 2015). Brady (2015) examines President Clinton’s attempt to massively overhaul health care in the United States. His plan, the Health Security Act (HSA), required employers to offer health insurance to their employees, and mandated that every US citizen purchase health insurance. This plan would have most likely expand health insurance to many more Americans; however, many feared the large tax increases, restricted options for patients, and with the lack of general support for the bill, it failed in Congress and was never implemented (p. 628). President Clinton’s failed attempt at health care reform opened up the door to future reforms, and it even shared multiple similarities to the PPACA. Smith (2015) updates the history of the health care system in America stating that â€Å"In the mid-2000s, America’s uninsured population swelled to nearly 47 million, representing about 16 percent of the population† and how â€Å"16 million Americans [†¦] were underinsured† (p. 2). 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